화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터)
권호 34권 1호
발표분야 의료용 고분자 부문위원회
제목 In Vitro Osteogenic Differentiation of Adult Stem Cells
초록 Adult stem cells (ASCs) have been shown to differentiate toward the osteoblastic lineage in vitro and in vivo upon stimulation with several osteogenic factors. ASCs possess the low immunogenicity and are able to escape from immune response. We herein examined the bone formation from adipose tissuederived stem cells (ADSCs) and rat muscle-derived stem cells (rMDSCs) in the presence of osteogenic medium. Osteogenic characteristics were identified by assaying for alkaline phosphatase (ALP) activity and by von Kossa staining for mineral nodules. We found that ALP and von Kossa stained expression of hADSCs and rMDSC grown in osteogenic medium was significantly higher than in cells grown in unsupplemented culture medium. Acknowledgements: This work was supported by a grant from MOST (No. M1064102000106N410200110).
저자 김이슬1, 김경숙2, 이주영3, 강윤미4, 이봉3, 민병현4, 김재호1, 이해방2, 김문석5
소속 1아주대, 2분자과학기술과, 3한국화학(연), 4나노바이오 융합연구센터, 5부경대
키워드 Adult stem cells
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