| 초록 |
Carbazole and its derivatives are highly potent materials for application in pharmaceutical medicine, organic light emitting diodes (OLEDs), organic field-effect transistors (OFETs) and functionalized polymer because of their specific electrochemical properties and biological activities. Although its derivatives are required in a wide range of fields, it is difficult to introduce functional groups into carbazole as a starting material. Therefore, most researchers have solved the problem by introducing functional group at desired position intentionally before the carbazole ring formation. Herein we have developed the three-step process for carbazole synthesis. Through this three-step process, we have achieved the synthesis of various carbazoles from in 10~48% overall yields. This process includes N-acetylation, copper(0) catalyzed Ullmann homocoupling reaction and acid-catalyzed intramolecular amination. All of the reagents using in the process are very cheap and commercially available |
