초록 |
To understand the mechanism underlying the function and dynamics of the nervous system or to treat neurological disorders, it is essential to develop the techniques capable of modulating and recording a diversity of signals employed by neurons. However, current approaches are limited in terms of effectiveness, side effects, non-specificity, and mechanical invasiveness. Naturally, there is a huge need for new devices or materials allowing for minimally invasive manipulation with monitoring of neural activity. My talk will introduce various complementary strategies to address these challenges: (1) Flexible and stretchable fiber-based probes for interfacing with the brain and spinal cord; (2) Biocompatible fiber scaffold to help the regeneration of neural tissue; (3) Wireless nanoparticle-based techniques for deep brain stimulation. These technologies enabling the interrogation with neural circuits across their diverse signaling modalities without inducing a foreign-body reaction helps the study of information processing as well as pathologies of the nervous system. |