초록 |
Recently, nanoparticles have received a great interest an application for diagnosis and therapy. Since nanoparticles possess intrinsic features that are often required for drug delivery system and diagnosis, they have potential as platforms for integrating imaging and therapeutic functions, simultaneously. Especially, molecular imaging with theragnostic nanoparticles makes it possible not only to provide useful information for monitoring drug delivery, drug release, and therapeutic efficacy of drug, but also to determine whether the patients are likely to respond to a therapy. To achieve these goals, a variety of imaging techniques have been used, including near-infrared fluorescent (NIRF) imaging, magnetic resonance imaging (MRI), nuclear imaging (SPECT and PET) and ultrasound imaging (US). |