화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU))
권호 19권 2호
발표분야 생체재료_포스터
제목  Investigation on the effects alendronic acid concentration on osteoblast growth in chitosan scaffold
초록  Chitosan is a polysacchride of D-glucosamine and N-acetyl-D-glucosamine. Chitosan is obtained from deacetylated chitin which is major component of arthropod exoskeleton. Chitosan is biocompatible, easily fabricated into a desired shape, and can improve cell immunity. Alendronic acid is used as a strong inhibitor of bone resoprtion in osteoporosis and increase bone affinity toward calcium ions so that can reduce bone fracture. In this study, we investigated the effects of alendronic acid concentrations on osteoblastic responses, including proliferation and differentiation. The physicochemical properties of the prepared scaffold, i.e chemical state and hydrophilicity, were analyzed.  
저자 이우걸, 김지혜, 이종호, 박창희, 허송이, 김주승
소속 단국대
키워드 Chitosan; Biocompatible; osteoporosis
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