화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center))
권호 21권 1호
발표분야 생체재료
제목 The effect of Epigallocatechin of Osteogenesis Evaluation of Duck’s feet-derived collagen/Hydroxyapatite Sponges
초록 Different ratios of epigallocatechin blended duck’s feet collagen (DC) sponges were fabricated followed by hydroxyapatite coating. Collagen is the main structural protein in extracellular space of various connective tissues in animal bodies and abundantly found in bones. Hydroxylapatite is a synthetic bone graft, which is the most used among other synthetic due to its osteoconduction, hardness and acceptability by bone. It has been observed that DC sponge with 50μm epigallocatechin showed improved cell proliferation and osteogenic differentiation. The composite material supports the cell growth and form hexagonal morphology with well-maintained functions. The samples were analyzed for various properties such as like, SEM, Porosity, FTIR, MTT assay, ALP assay, mRNA expression, in vivo test, etc. Results suggest that incorporation of epigallocatechin with duck’s feet collagen sponge can be potentially applied in bone transplantation
저자 국연지, 전하얀, 전경문, 최민정, 송정은, Nirmalya Tripathy, 강길선, 전유신
소속 전북대
키워드 Duck’s feet-derived collagen; Hydroxyapatite; Epigallocatechin; Osteogenesis
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