| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO)) |
| 권호 |
22권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Multiple Quantum dots Embedded Nanostructure for High Sensitive Detection Platform |
| 초록 |
In this study, we prepared simple, high sensitive and broad dynamic detection system based on quantum dots (QDs) embedded silica nanoparticles (QD2) and magnetic bead assembled immuno-complex is presented. The QD2s, which consists of multiple QDs, showed a 1,000 times stronger photo-luminescence (PL) than normal QDs and also modified ligand easily on their surface. As a model study based on biotin-streptavidin interaction, streptavidin can be detected in the range of 100 zM to 1 uM. When the system was applied to avian virus (H1N1 influenza virus) detection, 32 x 10-5 hemagglutination unit (HAU) to 3.2 HAU can be detected by system. This result is 520 times more sensitive than hemagglutination method and comparable with PCR. Because our system could detect target sensitively without amplifying step, it have great potential to application at bio-chemical field. |
| 저자 |
김태한, 김형모, 함은일, 강은지, 하유나, 전봉현
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| 소속 |
건국대 |
| 키워드 |
Quantum dots; high sensitive; sandiwich immuno-assay
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| E-Mail |
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