| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Improving tumor-targeting efficiency and anti-tumor effect based on the photothermal material laden stem cells |
| 초록 |
In this study, we have proven that a combination of hMSC and pRGO can enhance both tumor-targeting efficiency and PTT in a synergistic manner. The pRGOs might prevent the self-aggregation that could interfere with hMSC-loading efficiency. As a result, pRGOs were able to efficiently increase the surrounding temperature with NIR absorption. Combining pRGOs with hMSCs enhanced the tumor-targeting efficiency up to 2.5 times compared to conventional treatment. The synergistic effect induced by combining hMSCs and pRGO might contribute to a new platform for future photothermal therapy with a reduced number of particles and enhanced tumor-targeting efficiency. |
| 저자 |
이상호, 방석호
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| 소속 |
성균관대 |
| 키워드 |
Human mesenchymal stem cell; Photothermal cancer therapy; Poloxamer-reduced graphene oxide
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| E-Mail |
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