| 학회 | 한국공업화학회 |
| 학술대회 | 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 26권 1호 |
| 발표분야 | 포스터-생체재료 |
| 제목 | Effect of polycaprolactone surface-modified by plasma reactive ion etching on osteogenic differentiation of mesenchymal stem cells |
| 초록 | Plasma Reactive Ion Etching (RIE) is an effectivetechnique to positively modify the surface of biomaterials for cellularresponse. In thisstudy, the polycarprolactone (PCL) surface was modified through RIE, and thenthe surface properties and osteogenic differentiation of mesenchymal stem cells(MSCs) were investigated. The RIE process was carried out 3, 5 and 10 min atpower 100 W, pressure 100 mTorr, O2 flow rate 100 sccm. O2 level on thePCL surface was confirmed with XPS analysis, and surface roughness andwettability were verified with AFM and contact angle. The PCL surface modifiedby RIE showed the increase of surface roughness and wettability. The MSCsproliferation and migration were improved by RIE. Western blot result showedthat the levels of osteogenic markers were increased by RIE. Taken together,RIE-treated PCL material improves biocompatibility, and positively affect toosteoblast differentiation. (No. NRF- 2021R1A4A1030243). |
| 저자 | 배인호, 김희연, 석지훈, 김병훈 |
| 소속 | 조선대 |
| 키워드 | Polycaprolactone; Plasma reactive ion etching; Osteogenic differentiation; Mesenchymal stem cell |
