| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Preparation of Syndiotactic Poly(vinyl alcohol)/Platinum Nanocomposite Microspheres Using Suspension Copolymerization and Heterogeneous Saponification |
| 초록 |
Commercial PVA embolic particles such as ContourTM and Ivalon® have been obtained by the pulverization of a fully saponified PVA sponge. However irregularity of particles size and shape have caused an inflammatory reaction in the wall of the embolized vascular tissue and made it difficult to occlude targeted blood vessels selectively. Therefore, uniform particles size, spherical morphology and stability to human blood should be required. If embolic materials have proper radiopacity, their localization in and progress through the blood vessel can be more effective. To make Poly(vinyl pivalate/vinyl acetate) [P(VPi/VAc)] microspheres with radiopacity, radiopaque materials such as Pt were added into P(VPi/VAc) microspheres. The suspension copolymerization approach in the presence of aqueous radiopaque Pt was used. After, s-PVA/Pt nanocomposite microspheres were prepared through the heterogeneous surface saponification of P(VPi/VAc)/Pt nanocomposite microspheres. |
| 저자 |
차진욱1, 곽건영1, 이해규2, 노석균1, 제갈영순3, 류원석1
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| 소속 |
1영남대, 2서울 성모병원 영상의학과, 3경일대 |
| 키워드 |
keywords: embolization; radiopacity; syndiotactic poly(vinyl alcohol); Pt
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| E-Mail |
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