| 초록 |
Ceramic-based 3D printing techniques have opened new avenues for the designing and production of porous ceramic scaffolds with significantly improved mechanical properties combined with excellent bone regeneration abilities in vivo. More specifically, these techniques can construct tightly controlled porous structures (e.g., 3D periodic pores with perfect pore interconnectivity) by means of the selective consolidation of ceramic-based layers according to predetermined computer aided design (CAD) files. Thus far, a variety of 3D printing techniques have been developed for the production of porous ceramic scaffolds, including direct-ink-write assembly, 3D deposition/robocasting, extrusion freeforming, freeze-form extrusion fabrication, 3D printing, and stereolithography/digital light processing. I will introduce our ceramic/camphene-based 3D co-extrusion (3D-CoEx) as a new type of 3D printing techniques, which was recently developed by our group. Unlike conventional 3D printing techniques, our 3D Co-Ex technique can create highly aligned microporous ceramic filaments by utilizing camphene as a pore-forming agent. This innovative approach enables the production of ceramic scaffolds with controlled macro/micro-porous structures that can mimic the hierarchical architecture of natural bone on both the macro- and micro-scales. I will introduce a variety of macro/micro-porous designs which can be achieved using 3D Co-Ex technique, including unidirectional macrochannels with highly aligned microporous ceramic walls, 3-dimensionally interconnected macropores with microporous ceramic frameworks, and 3-D macropores with microporous hollow filaments. |
