| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 |
21권 1호 |
| 발표분야 |
생체재료 |
| 제목 |
Preparation of furfuryl chitosan derivative to prevent post-operation adhesion |
| 초록 |
Chitosan is a natural polymer that has beneficial properties such as less toxic, biodegradable, and biocompatible than synthetic polymers. Visible light-curable furfuryl chitosan derivatives(F-LMC) had been prepared by introducing furfuryl groups to amino groups of low molecular weight chitosan to prevent post-operation adhesion. The prepared F-LMC was characterized by 1H NMR and GPC analysis. Photo curing of F-LMC is occurred by a photo-oxidation-induced cross-linking mechanism. The cross-linking was determined by concentration of F-LMC and time of exposure to visible light. The cytotoxicity test using fibroblast 3T3 showed no toxicity of F-LMC. Cross-linked F-LMC surface inhibited cell adhesion. Prepared F-LMC is a novel candidate to prevent post-operation adhesion. |
| 저자 |
김재원, 한가득, 노승현, 김신웅, 손태일
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| 소속 |
중앙대 |
| 키워드 |
furfuryl chitosan derivatives(F-LMC); visible light; Post-operation adhesion
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| E-Mail |
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