학회 |
한국공업화학회 |
학술대회 |
2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO)) |
권호 |
22권 1호 |
발표분야 |
생체재료_포스터 |
제목 |
Application of visible light curable Furfuryl-Low molecular chitosan derivative as biomedical materials |
초록 |
Chitosan is a natural polymer that has beneficial properties such as less toxic, biodegradable, and biocompatible than synthetic polymers. Visible light-curable furfuryl chitosan derivatives(F-LMC) had been prepared by introducing furfuryl groups to amino groups of low molecular weight chitosan to prevent post-operation adhesion. The prepared F-LMC was characterized by 1H NMR and GPC analysis. Photo curing of F-LMC is occurred by a photo-oxidation-induced cross-linking mechanism. The cross-linking was determined by concentration of F-LMC and time of exposure to visible light. The cytotoxicity test using fibroblast 3T3 showed no toxicity of F-LMC. Cross-linked F-LMC surface inhibited cell adhesion. Prepared F-LMC is a novel candidate to prevent post-operation adhesion. |
저자 |
김신웅, 이태훈, 손태일
|
소속 |
중앙대 |
키워드 |
furfuryl chitosan derivatives(F-LMC); visible light; Post-operation adhesion
|
E-Mail |
|