화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO))
권호 22권 1호
발표분야 생체재료_포스터
제목 Application of visible light curable Furfuryl-Low molecular chitosan derivative as biomedical materials
초록 Chitosan is a natural polymer that has beneficial properties such as less toxic, biodegradable, and biocompatible than synthetic polymers. Visible light-curable furfuryl chitosan derivatives(F-LMC) had been prepared by introducing furfuryl groups to amino groups of low molecular weight chitosan to prevent post-operation adhesion. The prepared F-LMC was characterized by 1H NMR and GPC analysis. Photo curing of F-LMC is occurred by a photo-oxidation-induced cross-linking mechanism. The cross-linking was determined by concentration of F-LMC and time of exposure to visible light. The cytotoxicity test using fibroblast 3T3 showed no toxicity of F-LMC. Cross-linked F-LMC surface inhibited cell adhesion. Prepared F-LMC is a novel candidate to prevent post-operation adhesion.
저자 김신웅, 이태훈, 손태일
소속 중앙대
키워드 furfuryl chitosan derivatives(F-LMC); visible light; Post-operation adhesion
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