| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
기능성 고분자 (포스터발표만 진행) |
| 제목 |
Evaluation on effectiveness for preventing post surgical adhesion of γ-Cyclodextrin-Silk Fivroin / Carboxymethylcellulose (γ-CD/CMC) hydrogel in rat cecum/peritoneum |
| 초록 |
Polymeric hydrogels long gave attracted interest for biomaterials applications because of their generally favorable biocompatibility. γ-CD-SF/CMC hydrogels were prepared by reaction of carboxymethylcellulose (CMC) with silk fibroin (SF) capsulated by γ-cyclodextrin (γ-CD). The reaction was carried out in DW by variety concentration γ-CD-SF/CMC (w/w) ratio. The hydrogel formation is based on dehydration condensation reaction induced by self-assembling with no chemical crosslinking reagent involved. The structure of the hydrogels was confirmed with X-ray diffraction and their swelling, degradation, MTT assay and gel strength were measured. The γ-CD-SF/CMC hydrogel resulted in less adhesion than either pure hydrogel and could be used as a physical barrier to prevent abdominal post-operative adhesion during healing. |
| 저자 |
주유경1, 김진1, 이창문1, 김동운2, 이기영1
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| 소속 |
1전남대, 2광양보건대 |
| 키워드 |
γ-Cyclodextrin; Carboxymethylcellulose(CMC); Silk Fivroin; Hydrogels; Post-operative adhesion;
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| E-Mail |
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