| 학회 |
한국재료학회 |
| 학술대회 |
2018년 가을 (11/07 ~ 11/09, 여수 디오션리조트) |
| 권호 |
24권 2호 |
| 발표분야 |
2. 생체재료와 조직재생(Biomaterials and Tissue Regeneration)-오거나이저: 이병택 교수(순천향대) |
| 제목 |
Medical Device for Hard Tissue Regeneration |
| 초록 |
Biodegradable implants have been extensively studied for hard tissue regeneration. Magnesium seems as a potential candidate due to its unique combination of bone-like mechanical properties and being degradable in vivo. However, the rapid corrosion of magnesium and its alloys in physiological environment limits their clinical applications. Surface coatings are the reliable and the simplest way to improve corrosion resistance by preventing its contact with the environment. The present paper details the state of the art in coating and surface modification technologies, applied to magnesium alloys for improved corrosion resistance and biocompatibility. Single layered bioactive ceramic Ca-P based coatings and duplex ceramic-polymer based coatings are studied in this regard. The morphology, phase, chemical composition, wettability and performance in terms of in-vitro corrosion and biocompatibility using pre-osteoblast MC3T3 cells were discussed and compared with uncoated samples. Preliminary in-vivo performance using rabbit model for 2 weeks was also evaluated for the coatings with respect to magnesium substrate. |
| 저자 |
Preeti Makkar1, Byong Taek Lee2
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| 소속 |
1Institute of Tissue Regeneration, 2College of Medicine |
| 키워드 |
Magnesium alloy; Coatings; Corrosion; Biocompatibility; Biodegradable
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| E-Mail |
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