화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO))
권호 25권 2호
발표분야 포스터-환경·에너지
제목 Preparation of antifouling regenerated cellulose ultrafiltration membrane for protein separation in biopharmaceutical process
초록 Cellulose acetate (CA) membranes have been widely used in water purification processes due to their ease of processibility, non-toxicity, and chlorine stability. In particular, base hydrolysis of CA can induce antifouling regenerated cellulose (RC) membranes, but the detailed fabrication protocols are still elusive. In this work, we report the effects of hydrolysis conditions as well as beneath support layers in the resultant RC membranes. The acetyl groups (-CH3) in precursor CA membranes could be substituted to the hydroxyl groups (-OH) after immersed in aqueous NaOH solution. The degree of substitution was improved as increasing the hydrolysis time, confirmed by FT-IR, SEM, and contact angle analyses. In addition, a thin (< 10 μm) of RC layer was successfully coated onto a highly porous non-woven polypropylene support. Ultimately, the prepared RC membranes displayed a superior ultrafiltration (UF) performance compared to the pristine CA membranes with excellent fouling resistance.
저자 강준혁, 이태훈, 박호범
소속 한양대
키워드 cellulose acetate; regenerated cellulose; ultrafiltration; protein separation
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