| 학회 |
한국재료학회 |
| 학술대회 |
2020년 가을 (11/18 ~ 11/20, 휘닉스 제주 섭지코지) |
| 권호 |
26권 1호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
Reactive Oxygen Species Scavenging and Improvement Effect of Inflammatory Disease Treatment by Functionalized Nanoparticles |
| 초록 |
Various types of nanomaterials are recently under research for diagnostic and therapeutic applications in the biomedical area while our information for their potential effects and fate in living cells is still limited. Also the interaction of nanoparticles with cellular functions, such as repression/activation of genes and activation of specific cell organelle. Here we demonstrate for the ceria-zirconia nanoparticles (CZNPs) that localize intracellular organelle could effectively reduce reactive oxygen species (ROS) as a result of the improvement effect of inflammatory disease. It this process, CZNPs are faster change from Ce4+ to Ce3+ than those indicated by another ROS scavenging nanoparticles. These research has significant consequences for understanding the nanotherapeutics for the treatment of diseases. |
| 저자 |
홍상은, 윤국노
|
| 소속 |
한남대 |
| 키워드 |
<P>Ceria-Zirconia Nanoparticles; Reactive Oxygen Species; Organelle; Inflammatory disease</P>
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| E-Mail |
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