| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 봄 (04/30 ~ 05/02, 제주국제컨벤션센터) |
| 권호 |
18권 1호 |
| 발표분야 |
생물화학기술의 진보와 전망 |
| 제목 |
Biosynthesis of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from butyrate using engineered Ralstonia eutropha |
| 초록 |
Polyhydroxyalkanoates (PHAs), a promising family of bio-based polymers, are considered to be alternatives to traditional petroleum-based plastics. Copolymers like poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(HB-co-HHx)) have been shown to exhibit favorable physical and mechanical properties, due to decreased crystallinity resulting from the presence of medium chain length 3-hydroxy hexanoate (3HHx) monomers. In this study, we produced P(HB-co-HHx) using engineered Ralstoniaeutrophastrains using butyrate, a short-chain organic acid, as the carbon source. Although the wild type R. eutropha did not produce P(HB-co-HHx) when grown on mixed acids or on butyrate as the sole carbon source,we are able to produce up to 40 wt% 3HHx monomer using various concentrations of just butyrate as the sole carbon source. |
| 저자 |
양영헌1, 전종민1, 김현중1, 김용현1, 이다혜1, 이주희1, Brigham CJ2
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| 소속 |
1건국대, 2Department of Bioengineering |
| 키워드 |
PHA; butyrate
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| E-Mail |
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