화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center))
권호 24권 1호
발표분야 포스터-생물공학
제목 Enzymatically Synthesized DNA-Metal Microstructures
초록 As DNA engineering advances, there have been many reports regarding DNA incorporated with other functional materials. However, there are only a few inorganic materials incorporating DNA reported due to their lack of manipulability and predictability. To address the issue, we report a strategy for the synthesis of DNA-inorganic hybrids. In this study, we introduce the rolling circle amplification (RCA) technique with the supply of metal ions for in situ production of the DNA-metal hybrid structures in the amplification process. The features of the products could be easily controlled by changing types of metal ions. In particular, DNA-Mn particles can facilitate a wide range of functions as a cell tracking agent, a contrast agent, or supercapacitors. This study will shed light on materials made of organic-inorganic superstructures for biomedical and even electrochemical systems.
저자 지윤빈, 이제성, 이종범
소속 서울시립대
키워드 DNA; enzymatic synthesis; organic-inorganic hybrid composites; rolling circle amplification
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