화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터)
권호 42권 1호
발표분야 의료용 고분자 부문위원회 I
제목 A Release Study Of Sarpogrelate Tablets.
초록 Sarpogrelate is used alone or with other medicines to treat Chronic arterial occlusion. Improvement of ischemic symptoms such as ulceration, pain and coldness caused by chronic arterial occlusion (Burger's disease, occlusive atherosclerosis, diabetic peripheral vascular disease, etc.) SEM was used to observe the dissolution behavior of Sarpogrelate tablet. Crystallinity of Sarpogrelate, additives and Sarpogrelate tablet was analyzed by using DSC. XRD was used to analyze the change of crystalline state between Sarpogrelate, additives and valsartan tablet. The in vitro test was carried out to confirm whether Sarpogrelate tablet is soluble in intestinal juice. The in vitro test found sustain-release of Sarpogrelate tablet.
저자 박현, 최욱균, 박종호, 김창현, 전성현, 송정은, 이대훈, 강길선
소속 전북대
키워드 Sarpogrelate; Solid Dispersion; Rotary Evaporation.
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