| 학회 |
한국화학공학회 |
| 학술대회 |
2015년 봄 (04/22 ~ 04/24, 제주 ICC) |
| 권호 |
21권 1호, p.822 |
| 발표분야 |
재료 |
| 제목 |
Fabrication of highly sensitive uric acid biosensor based on directly grown ZnO nanosheets on electrode surface |
| 초록 |
Here we report the direct synthesis of ZnO nanosheets (ZnO NSs) on the electrode surface by one step low temperature solution process and characterized in detail using various techniques. The directly grown ZnO NSs used for fabrication of uric acid biosensor and performance of fabricated has been examined for uric acid detection. This biosensor showed high sensitivity of 129.81 μA cm-2 mM-1 in wide-linear range (0.05-2.0 mM) with high R2 of 0.9993. A rapid response time of ~5s, low detection limit of 0.019 μM (based on S/N ratio) and lower value of Kmapp (0.026 mM) was calculated, which shows a high affinity between the uric acid and uricase immobilized on ZnO NSs. The anti-interference ability, reproducibility and long-term storage stability of biosensor were examined. These results suggests that our fabricated biosensors are highly reproducible, selective and stable for favorable determination of uric acid and can be effectively used for application in real samples with good precision and accuracy. |
| 저자 |
Ahmad Rafiq1, Nirmalya Tripathy2, 박용규3, 한윤봉1
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| 소속 |
1전북대, 2Department of BIN Fusion Technology, 3Chonbuk National Univ. |
| 키워드 |
ZnO nanosheets; biosensor; uric acid; uricase; high sensitivity
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| E-Mail |
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| 원문파일 |
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