화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터)
권호 38권 1호
발표분야 의료용 고분자 부문위원회
제목 Synthesis of Various Size Iodine-PEG capped Gold Nanoparticles for Computed Tomography Contrast Agent
초록 Gold nanoparticles (AuNPs) are a fascinating material because of their controllable biointerfacial properties, low cytotoxicity, and high X-ray absorption. For these reasons, AuNPs have attracted scientists’ attention who developed AuNPs as a computed tomography (CT) contrast agent. In this study, we developed biocompatible AuNPs with various size for a CT contrast agent. Seed-mediated synthesis of AuNPs and the surface modification with PEG were used to produce stable AuNPs with increased CT detection sensitivity. The feasibility of biocompatible AuNPs as a CT contrast agent was tested In vitro using CT and it showed promising results as a CT contrast agent.
저자 이성훈1, 선인철2, 김정연3, 김동억3, 김광명2, 안철희1
소속 1서울대, 2한국과학기술(연), 3동국대
키워드 gold anoparticle; computed tomography; iodide
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