화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2015년 봄 (04/29 ~ 05/01, BEXCO (부산))
권호 19권 1호
발표분야 생체재료_포스터
제목 Fluorescent Carbon Nanoparticle Derived from Hyaluronic Acid for Cancer Targeted Imaging
초록 Cancer targeted biocompatible bio-imaging carrier has the potential to revolutionized diagnosis and therapy. To address these potentialities, we report in situ synthesis of hyaluronic acid fluorescent carbon nanoparticle (HA-FCN) and fluorescent carbon nanoparticle (FCN) obtain from the controlled carbonization method using the biocompatible hyaluronic acid (HA). The FCN with remaining HA (HA-FCN) and without identification of remaining HA (FCN) both showed aqueous solubility and small particle size (<20 nm) with different in fluorescence intensity. Without typical conjugation, HA-FCN itself appeared for the trigger targeted bioimaging for the probe. These findings speculate outstanding features in new drug delivery, sensors, diagnostic tools and different biomedical application.
저자 Shazid Md. Sharker1, 김성한2, 이해신1, 박성영2
소속 1KAIST, 2한국교통대
키워드 Hyaluronic Acid; Fluorescence Carbon Nanoparticle; Bio-imaging; Biocompatibility; Target delivery.
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