| 학회 | 한국공업화학회 |
| 학술대회 | 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 22권 2호 |
| 발표분야 | 정밀화학_포스터 |
| 제목 | Changes of Fluorescence quenching by Structural Difference |
| 초록 | Tryptophan is one of aromatic amino acids and well known as a fluorescence quencher with PET mechanism. To make tryptophan to have an effective quenching ability, we can induce Van der Waals force between tryptophan and a fluorophore with introduction of a short peptide chain. This fluorescence quenching ability changes by the distance of two residue, and can be figured out by the peptide chain. Herein, we developed a series of fluorescence sensors based on NBD as a fluorophore and tryptophan as a receptor connected with different length of glycine chains for detection of mercury ions. These sensors detect mercury ions selectively either by turn on or turn on response depending on the length of linkers between the NBD and the tryptophan part. |
| 저자 | 정재욱, 이건형 |
| 소속 | 인하대 |
| 키워드 | NBD; Tryptophan; quenching; mercury |
