| 초록 |
In this study, on the surface of GO@SiO2@Ag NPs@MPBA silver nanoparticle embedded silica coated graphene oxide (silver nanoparticle embedded silica coated graphene oxide), 4-MPBA (4-mercaptophenyl boronic acid) was self-assembled to detect glucose by SERS (surface enhanced Raman scattering). The SERS intensity of 4-MPBA on the GO@SiO2@Ag nanoparticles was 2.2-fold higher than that of GO@Ag nanoparticles. Furthermore, silica-coated graphene oxide revealed lower background signal compared to graphene oxide. The SERS intensity of GO@SiO2@Ag NPs@MPBA peaked at 1 mM 4-MPBA. The pH-dependent behavior of 4-MPBA was investigated with GO@SiO2@Ag NPs, and the highest SERS signal intensity was detected at pH 3. Glucose binding to 4-MPBA integrated GO@SiO2@Ag NPs increased the SERS signal at both 1,072 and 1,588 cm-1. The linear range was estimated to be 2-20 mM glucose. It is the result of insights for the development of SERS-based biosensors using glucose detection and graphene oxide. |
