화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2012년 가을 (10/24 ~ 10/26, 부산 BEXCO)
권호 18권 2호, p.1736
발표분야 분리기술
제목 “Backfill” Strategy for Improving the Separation Performance in Simulated Moving Bed Chromatography
초록 Simulated moving bed (SMB) is a continuous chromatographic separation process and it has been adapted to the petrochemical, fine chemistry and pharmaceuticals. In a conventional SMB, the majority of impurity component for each product node emerged on one side in a switching period. Therefore, many operating strategies improved the separation performance of SMB by periodic modulation of certain operating parameters during a switching period such as VariCol, Partial-feed, ModiCon, and OSS SMB.  
In the previous work, our group suggested the Partial-Discard (PD) and Recycling Partial-Discard (RPD) operations from discarding and re-feeding the part of impurity in the product. As another re-feeding process, the product was re-fed to the SMB circuit in the “Backfill” operation in this work. Several methods of re-feeding were introduced and compared in the “Backfill” operation. And from the results, the guide line for “Backfill” operation design was suggested.
저자 김경민, 이창하
소속 연세대
키워드 Simulated Moving Bed; Backfill
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