초록 |
Molecular imaging has suffered from limited applications due to the short light penetration depth. Here, we developed mechanoluminescent (ML) particles that can non-invasively emit light in the deep tissue upon non-destructive ultrasound (US) stimulation. ML particles were synthesized through solid state reaction of ZnS:Ag, Co. In the photoluminescence spectra, two emission peaks were detected at 450 nm and 540 nm. ML particles, recharged with UV light, could emit concentrated light with US stimulation. Taken together, it has been demonstrated that synthesized ML particles could effectively trap light and emit intense light in response to US for molecular imaging applications. |