| 초록 |
Stimuli-responsive copolymers have been studied for smart drug delivery systems. There are various stimuli such as, temperature, pressure, pH, and so on; however, light is the most attractive stimulus because the intensity, wavelength, localization and fast fluctuation (in case of reversible responsiveness) of light stimulus are easily controlled. In this work, styrene, N-isopropylacrylamide (NIPAAm), and spironaphthoxazine methacryloyl (SPO) monomers were used for the preparation of block copolymers in reversible-addition fragmentation chain transfer (RAFT) polymerization. The copolymers were then used for UV light-responsive vesicles fabricated in a microfluidic device. The properties of the copolymers and corresponding vesicles will be discussed in the presentation. |
