| 초록 |
Quinone tanning is a chemical crosslinking reaction mediated by oxidized catechols, also called quinones. Nature employs this reaction to synthesize polymeric networks such as insect cuticle, squid beak, and melanin pigment. It has been reported that sol-gel transition and/or pigmentation of catecholic precursors by quinone tanning can be utilized as a readout signal for rapid and convenient biomarker detection through the naked-eye. In particular, the unique optical and adhesive properties of polymerized catecholic materials provide spatial information of biomarkers in addition to quantitative analysis, making them powerful molecular probes. In this talk, our recent approaches to spatially and temporally initiate quinone tanning in biomarker-specific manner will be discussed. |
