초록 |
The long-term bidirectional peripheral neural interface was considered as powerful tool for neural prosthetic for amputated or paralyzed people. It has been developed in non-invasive method, the cuff electrode. However, the cuff electrode still has problems, owing to their mechanical modulus mismatch, such as blockage, and immune responses which prevents accurate long-term signal recording. Moreover,the fixation tools (e.g. suturing) must be used to lock up the electrode on nerve but they cause device failure or tissue damage. Here in, we describe a self-healing electronic epineurium, which can form stress-free and strain-insensitive device and enable facile bio fluid-resistant self-locking owing to dynamic stress relaxation and water-proof self-bonding properties. We achieved a bidirectional neural signal recording and stimulation in a rat sciatic nerve for 14 weeks. Our technology would be considered a new implantable platform for implantable electronics for peripheral nerve. |