| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Sophisticated Plasmonic Nanomaterial as the Photo-Nanozyme for Dynamic Cancer Therapy under NIR Light |
| 초록 |
The utilization of nanomaterials as the nanozyme for dynamic cancer therapy received significant attention from the scientific community. Especially, the noble plasmonic nanomaterials have huge potential due to the intrinsic properties of noble metals, localized surface plasmon resonance (LSPR), and photothermal effect to not only induce the generation of reactive oxygen species (ROS) but also generate enough heat for cancer therapy. Herein, we synthesized uniform gold nanobipyramids, with selective deposition of palladium nanoparticles at the end. Upon laser irradiation, we observed significantly enhanced peroxidase-like activities of our materials due to facile collection of induced hot carriers at the incorporated Pd centers. Also, LSPR induced thermal effect was incorporated to our system to induce synergistic photothermal and dynamic therapy. Our work highlights the ability of this novel and highly efficient hybrid nanocomposite as a NIR-responsive tumor catalytic therapy. |
| 저자 |
유수빈1, 김동하1, 장도협2, 김세훈2, Jianfang Wang3
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| 소속 |
1이화여자대, 2KIST, 3The Chinese Univ. of Hong Kong |
| 키워드 |
nanozyme; peroxidase-like activity; plasmonics; photodynamic cancer therapy
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| E-Mail |
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