| 학회 |
한국재료학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 광주 김대중컨벤션센터) |
| 권호 |
27권 1호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
Cellulose Nano Crystal Reinforced Ca/P Based Injectable Bone Substitute with Enhanced Biocompatibility |
| 초록 |
Injectable bone substitutes showed great potential as bone tissue engineering scaffolds for their better biocompatibility, injectability and interconnected porosity which favors loading bioactive substances. Now a day’s usage of cellulose as an alternative candidate to synthetic polymers might allow the decrease of environmental impacts by attaining more simply biodegradable or reusable materials. Lately, cellulose nano crystals (CNC) are synergistically attached to functional materials to achieve better performance. CNC, can be obtained through a mechanical or chemical treatment on plant cell walls, having a low density and a high specific surface area and shows high tensile strength and elasticity. These characteristic features of CNCs are attracting researchers to use as a reinforcing agent to increase the strength of composite materials. The current article presents the trials for preparing CNC/CaP hybrid materials and offer prospects for many applications in tissue regeneration. In the present study we described a method to produce an injectable bone substitute consisting of a solid and liquid phase, the solid phase is formed using mixture of CNC laden beta-tricalcium phosphate (β-TCP). The characterization of the composite was performed by FTIR spectroscopy, X-ray diffraction ,scanning electron microscopy and mechanical behavior using UTM. In vitro biological evaluations have also been conducted to confirm the bio-ability of the developed bone substitute. |
| 저자 |
Garima Tripathi1, Byong-Taek Lee2
|
| 소속 |
1Institute of Tissue Regeneration, 2College of Medicine |
| 키워드 |
cellulose nanocrystal; β-TCP; brushite
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| E-Mail |
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