| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Aggregation enhanced two-photon absorption dyes for in vivo imaging |
| 초록 |
In this work we are investigating the synthesis, characterization and application of aggregation enhanced two-photon absorption (TPA) dyes. This non-linear effect can be used for many applications as for example 3D-microfabrication, bioimaging, etc. Typically near infrared light for two-photon absorbing behavior is used for excitation of organic chromophores. Biological tissue show high transmissions in these wavelengths which renders TPA based bioimaging ideal for in vivo monitoring. Using J-Aggregation and Eximer-Formation it is possible to gain aggregation enhanced fluorescence. Based on this knowledge, our research goal is to synthesize new four TPA dyes with high efficiency based on a 3,3'-(thiophene-2,5-diyl)bis(2-(4-bromphenyl)acrylonitrile) core using different electron-donor groups and apply these within PEGylated phospholipid nanomicelles for in vivo monitoring of cancer cells. |
| 저자 |
채하늘1, Tobias Johann2, Kerstin Schmidt2, 박진순1, 이광섭1
|
| 소속 |
1한남대, 2Johannes Gutenberg-Univ. |
| 키워드 |
TPA; Bioimaging
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| E-Mail |
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