초록 |
Recent studies have sought to chemically control and tailor the metabolic behaviors of non-spore-forming cells, as well as enhancing their viability against adverse environmental conditions, by forming thin (< 100 nm), tough artificial shells. These living “cell-in-shell” structures, called artificial spores (chemically-formed spore-like structures), enable control of cell division, protection against physical and chemical stresses, and cell-surface functionalizability, as well as providing the cells with exogenous properties that are not innate to the cells but are introduced chemically, such as magnetism, heat-tolerance, and UV-resistance. In this talk are discussed chemical approaches, including layer-by-layer self-assembly and metal-organic films, to individually encapsulate living cells within thin and tough shells with the aim of creating artificial spores. |