| 초록 |
Photoacoustic (PA) imaging is very promising technique, based on the generation of ultrasonic wave after irradiation of a light to a material. PA signal has high resolution and great penetration depth, because the degree of ultrasonic scattering is lower than that of fluorescence. Therefore, it is known to be very powerful tool for in vivo imaging. On the other hand, SERS nanoprobe is continuously receiving high attention as an outstanding nanomaterial for multiplexed detection of target bio molecule. SERS signals do not have photobleaching problem, and have much narrower peak width than fluorescence. Herein, we have synthesized near-IR nanoprobe which can generate both PA and SERS signals. The nanoprobe is biocompatible due to the hydrophilic surface modification, and is expected to be an effective tool for in vivo imaging and multiplexed detection. |
