학회 | 한국공업화학회 |
학술대회 | 2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
권호 | 25권 1호 |
발표분야 | 포스터-생물공학 |
제목 | Platform for the biorefinery of brown macroalgae; Vibrio sp. dhg |
초록 | Brown macroalgae holds potential as an alternative feedstock. But its utilization by conventional microbial platforms has been limited due to the inability to metabolize one of the principal sugars, alginate. Here, we isolate Vibrio sp. dhg, a fast-growing bacterium that can efficiently assimilate alginate. Based on systematic characterization of the genomic information of Vibrio sp. dhg, we establish a genetic toolbox for its engineering. We also demonstrate its ability to rapidly produce ethanol, 2,3-butanediol, and lycopene from brown macroalgae sugar mixture with high productivities and yields. Collectively, Vibrio sp. dhg can be used as a platform for the efficient conversion of brown macroalgae sugars into diverse value-added biochemicals. |
저자 | 오정수1, 임현규1, 곽동훈1, 박성우2, 우성화1, 정규열1 |
소속 | 1POSTECH, 2서울대 |
키워드 | biorefinery; brown marco-algae; Vibrio sp. dhg |