| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
Efficient lycopene Production in Escherichia coli by engineering Two MEP Pathway Enzymes from Vibrio sp. dhg |
| 초록 |
Bio-based chemical production is a promising method that can overcome major limitations in conventional methods of lycopene production, such as low yields and variations in product quality. Significant efforts have been made to improve lycopene production by engineering either the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway or mevalonate (MVA) pathway in microorganisms. To further improve lycopene production, it is critical to utilize metabolic enzymes with high specific activities. Two enzymes, 1-deoxy-d-xylulose-5-phosphate synthase (Dxs) and farnesyl diphosphate synthase (IspA), are required in lycopene production using MEP pathway. Here, we evaluated the activities of Dxs and IspA of Vibrio sp. dhg, a newly isolated and fast-growing microorganism. |
| 저자 |
오정수, 김민재, 노명현, 우성화, 임현규, 정규열
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| 소속 |
POSTECH |
| 키워드 |
Lycopene; MEP pathway; Metabolic engineering; Vibrio sp. dhg
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| E-Mail |
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