| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO)) |
| 권호 |
25권 2호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
Vibrio sp. dhg, a novel bacterial host for brown macroalgae refinery |
| 초록 |
Although brown macroalgae holds an enormous potential as an alternative feedstock, its utilization by conventional microbial platforms has been limited due to the inability to metabolize alginate, one of the major sugars. Here, we isolated Vibrio sp. dhg, a novel, fast-growing bacterium that can efficiently utilize alginate. Based on systematic characterization of the genomic information of Vibrio sp. dhg, we were able to develop a genetic toolbox for its engineering, and successfully demonstrated its ability to rapidly produce a broad spectrum of chemicals (ethanol, 2,3-butanediol, and lycopene) from brown macroalgae sugar mixtures with a high productivity. Collectively, Vibrio sp. dhg strain is a powerful platform for the conversion of brown macroalgae sugars whose usage will dramatically accelerate the production of value-added chemicals. |
| 저자 |
백동엽1, 임현규2, 곽동훈1, 박성우3, 우성화1, 양재성4, 강채원1, 김범희3, 노명현2, 서상우3, 정규열1
|
| 소속 |
1POSTECH, 2Univ. of California San Diego, 3서울대, 4Centre for Research in Agricultural Genomics |
| 키워드 |
Metabolic engineering; Brown macroalgae refinery; Vibrio sp. dhg
|
| E-Mail |
|
