화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO))
권호 22권 1호
발표분야 생체재료_포스터
제목 To Improve Regeneration of Corneal Endothelial Cells Using the Retinoic acid/ Silk Fibroin Film
초록 Silk fibroin (SF) is a natural material and it has various properties such as biocompatible, biodegradable, and transparent. Silk has good cell proliferation. Retinoic acid (RA) mediates the functions of vitamin A required for growth and development. Thus, this study was used RA/ SF scaffold for corneal endothelial cell regeneration. RA/SF Scaffolds were fabricated with 0, 25, 50, 75 and 100μM RA. The properties of RA/SF films were analyzed using MTT, RT-PCR, initial density, and transparency, contact angle. Overall results showed that incorporation of 75μM RA/SF can be positively applied as suitable alternative for high level corneal endothelial cell expansion and transplantation.
This research was supported by Basic Science Research Program (NRF-2017R1A2B3010270)
저자 김한솔, 신은영, 최민정, 김다윗, 강길선
소속 전북대
키워드 silk film; cornea
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