| 학회 | 한국화학공학회 |
| 학술대회 | 2009년 봄 (04/23 ~ 04/24, 광주 김대중컨벤션센터) |
| 권호 | 15권 1호, p.404 |
| 발표분야 | 생물화공 |
| 제목 | Cell chip based on polyaniline film coated indium-tin oxide electrodeto detect anticancer drug effect |
| 초록 | Polyaniline Emeraldine (EB) base coated Indium-Tin Oxide (ITO) electrode was prepared for the construction of a cell-based chip. Ultrathin polyaniline PANI film on an ITO was electroactive at neutral pH without co-deposition of an acidic counterion. HeLa cells were cultured on a PANI/ITO substrate and utilized to assess the biological toxicity of anticancer drugs. Cell growth, cell viability and drug-related cell toxicity were evaluated by a cyclic voltammetry (CV) method under a neutral pH. We demonstrated the functionality of a PANI coated ITO electrode for use as a cell chip and found that PANI was a good surface for the HeLa cells to grow without any significant morphological changes. Acknowledgments : This research was supported by Seoul R&BD Program(10816) and by the Nano/Bioscience & Technology Program (M10536090001-05N3609-00110) of the Ministry of Science and Technology (MOST) and by Ministry of Environment of the Republic of Korea as "The Eco-technopia 21 project". |
| 저자 | Waleed Ahmed El-Said1, 예철헌2, 최정우2 |
| 소속 | 1Interdisciplinary Program of Integrated Biotechnology, 2서강대 |
| 키워드 | cell chip; ITO; Polyaniline; drug effect |
| 원문파일 | 초록 보기 |
