| 초록 |
Reinforcing hydrogels could be achieved by adding solids. However, poor interfacial interaction between polymers and smooth solids causes sedimentation, and/or brittle fracture under stress. Herein, porous diatom silica (p-DS, Melosira nummuloides) and adhesive chitosan catechol (CHI-C) are entangled both chemically and physically, converting hydrogels to elastomeric ones. CHI-C/p-DS endures up to 60 % of compressive strain and ~400 % of area enlargement under biaxial tensile strain. Pore-infiltrated CHI-C crosslinks inside pores by oxidation, creating polymer/solid interlocking. CHI-C/p-DS protects the wound by dissipating energy and releases drugs in a mechanically controlled manner. With proper adhesion strength, CHI-C/p-DS dressing assists the initial healing of the pressure ulcer in a murine model. Categorized as 100% water-borne elastomers, CHI-C/p-DS elastomeric gel gives insight into the fabrication of elastomers and breakthroughs in smart dressing. |
