| 학회 |
한국공업화학회 |
| 학술대회 |
2009년 봄 (04/15 ~ 04/17, 호텔인터불고(대구)) |
| 권호 |
13권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Poly(N-isopropylacrylamide-co-methacrylic acid) stabilized nanoparticles |
| 초록 |
A novel nanoparticle was developed using poly(N-isopropylacrylamide-co- methacrylic acid) (P(NIPAM-co-MAA)) and N-[3-(dimethylamino)propyl]-octadecanamide (DMAPODA) by salt bridge which is pH-sensitive. According to the results, the critical association concentrations (CACs) of the nanoparticles increased with increasing the ratio of hydrophilic copolymer. Moreover, due to the pH-sensitivity of the salt bridges, the nanoparticles were pH-sensitive in terms of change in their size. The nanoparticles might be applicable to the delivery of therapeutic agents or genes. |
| 저자 |
YANG XIA, 권택관, 강미경, 홍연지, 김진철
|
| 소속 |
강원대 |
| 키워드 |
Lipid nanoparticles; Salt bridges; Stabilizer; Hydrophilic polymer
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| E-Mail |
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