화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU))
권호 20권 2호
발표분야 (국제협력) 우수 외국인 연구자 세션
제목 Coated Surface Phase Bacteria Detection Assay Using a Fluorescent Polymer
초록 We studied the combined design polymer to obtain dual functions for both detection and killing bacteria. Our integrated polyvinylpyrolidone (PVP) backbone with catechol and bromoethane moieties showed tunable fluorescence behavior due to the presence of boron dipyrromethane (BODIPY) and near infared NIR-responsive IR825 (F-PVP). The cationic segments showed distinct fluorescence quenching after interaction with gram-positive and negative bacteria via polyion complex interactions confirmed using SEM and confocal imaging with the detection limit 1 mg/mL for the liquid-phase assay. We demonstrated detection bacteria using coated surface polypropylene (PP) phase assay showing fluorescence quenching. The solid-phase assay can be used to detect bacteria much as litmus paper. More advances, this agent can directly kill bacteria via the photothermal conversion ability using NIR exposure. This study was supported by Korea National University of Transportation at 2016.
저자 Zihnil Adha Islamy Mazrad, 박성영
소속 한국교통대
키워드 Bacteria; Detection; Quenching; Coatable; Killing
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