| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Design of Tissue Adhesive Catechol-functionalized Thermos-responsive Hydrogels for Biomedical Application |
| 초록 |
Injectable and temperature-sensitive hydrogels were synthesized based on dopamine end-capped Pluronic (Plu-DP) and 2-chloro-3′,4′-dihydroxyacetophenone-quaternized poly[(dimethyl aminoethyl methacrylate)-co-(t-butylmethacrylate)] for tissue engginering material. The catechol -functionalized polymer crosslinked hydrogels exists in a viscous solution state at room temperature, but becomes a gel via in situ crosslinking at body temperature. This material is stable and the temperature-sensitive 14:8 wt% ratio and showed reversible sol-gel transition behavior within 10 s, presenting excellent mechanical properties and gel stability. In conclusion, this hydrogel can be applied for drug delivery and tissue engineering in biomedical application. This work was supported by Korea National University of Transportation in 2017. |
| 저자 |
Zihnil Adha Islamy Mazrad, 이운한, 박성영
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| 소속 |
한국교통대 |
| 키워드 |
Tissue adhesive; Catechol; Thermoresponsive; Injectable
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| E-Mail |
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