화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2013년 가을 (10/23 ~ 10/25, 대구 EXCO)
권호 19권 2호, p.1861
발표분야 재료
제목 High performance hybrid biosensor for simultaneous detection of glucose, cholesterol and urea based on ZnO nanorods field effect transistor arrays
초록 An integrated biological hybrid sensor based on the solution-gated field-effect transistors (FETs) was designed by growing three active zinc oxide nanorods arrays between the source-drain selectively on pre-patterned substrates, followed by the immobilization of glucose oxidase, cholesterol oxidase and urease enzymes on each array. The proposed hybrid biosensor has been used for the simultaneous and highly selective detection of glucose, cholesterol and urea without any interference in each sensor response. The hybrid sensor demonstrated wide-linear range, high sensitivity, favorable reproducibility and long-term performance stability. Compared to the analytically measured data, the performance of the FETs-based hybrid sensor was found to be highly reliable for rapid detection of multi-anlalyte not only in normal mice blood and serum samples, but also in blood samples collected from diabetic dogs. This simple convenient hybrid/integrated FETs biosensor was envisioned to set a potential platform for various disease management.
저자 Ahmad Rafiq1, Nirmalya Tripathy2, Yong-Kyu Park2, 한윤봉2
소속 1전북대, 2Chonbuk National Univ.
키워드 Zinc Oxide; Field-effect transistors; Glucose; Cholesterol; Urea
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