| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 20권 2호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Preparation of 3D porous elastic chitosan/poly(L-lactide-co-ε-caprolactone) scaffolds by acetylation reaction and particulate leaching method |
| 초록 | For soft tissue applications, 3-D porous acetylated chitosan/poly(L-lactideco-ε-caprolactone) (PLCL) scaffolds were prepared by acetylation and particulate leaching using sodium acetate as the porogen in an acidic water/dioxane solution. The enhanced physiochemical properties of acetylated chitosan/PLCL hybrid scaffolds were confirmed by measuring water contact angles, pore morphology and interconnectivity using scanning electron microscopy (SEM), and dye release testing. In addition, mechanical properties such as tensile strength and bending stress recovery for determining the elasticity of scaffolds were measured. The fibroblast cell line NIH-3T3 was used to test relative cell affinities for the acetylated chitosan/PLCL vs. normal chitosan/PLCL films and porous scaffolds.This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717) |
| 저자 | 임진익, 김주승, 정은진, 이수희, 이우걸 |
| 소속 | 단국대 |
| 키워드 | 3D porous scaffolds; acetylation reaction; particulate leaching method |
