| 초록 |
In order to prepare a photo-dependent liposome, Egg phosphatidylcholine (egg PC) liposome was coated acidic proteinoid having coumarin. Acidic proteinoid was synthesized by polymerization of amino acids such as glycine, arginine, serine and leucine at 160°C. Acidic proteinoid having coumarin (APC) was prepared by reacting the polymer with epoxypropoxy coumarin in a strong alkali condition. The release of 5(6)-carboxyfluorescein (CF) from egg PC liposome coated with APC was enhanced by irradiation of λ = 254 nm (6W), possibly due to the photo-dedimerization of epoxypropoxy coumarin residues of the acidic proteinoid. |
