| 학회 | 한국공업화학회 |
| 학술대회 | 2014년 가을 (11/12 ~ 11/14, 엑스코(대구)) |
| 권호 | 18권 2호 |
| 발표분야 | 정밀화학-포스터 |
| 제목 | Applications of Alkynyldimethylaluminum Reagents for the Synthesis of α,β-Alkynyl Ketones, 3-(N,N-Disubstituted Amino)-1,4-diynes and 1-ynes |
| 초록 | Organoaluminum reagents have proven as remarkable reagents in organic synthesis due to their inherent reactivity, wide range of applicability, low cost and commercial availability. Organoaluminum compounds can easily react with various heteroatoms in organic molecules, particularly with oxygen and nitrogen, even with carbon to form a strong coordinate complex (1:1). Micouin et al. has developed the alkynyldimethylaluminum reagent from the reaction of alkynes with trimethylaluminum using a catalytic amount of Et3N. We have utilized alkynylaluminum reagents for the synthesis of α,β-alkynyl ketones 3-(N,N-Disubstituted Amino)-1,4-diynes and 1-ynes. [Korbad, B.L and Lee, S.-H. Synlett 2013, 24, 1953] |
| 저자 | 이상협 |
| 소속 | 대구가톨릭대 |
| 키워드 | α; β-alkynyl ketones; trimethylaluminum |
