| 초록 |
Indoles are important heterocycles contained in many natural products, agrochemicals, and pharmaceuticals. Due to the importance and usefulness of C-arylindoles, a range of synthetic approaches have been developed based on the transition metal-catalyzed direct arylation of indoles with activated arenes and including the oxidative C-H coupling of indoles with nonactivated arenes also. But, there are few reports of direct C-C bond formation to construct functionalized naphthalene derivatives based on the indole nucleus. Herein, we present a Rhodium(II)-catalyzed diect arylation of indoles with 1-diazonaphthalene-2-(1H)-ones for synthesis of 3-naphthylindoles regioselectively. This procedure provides a range of novel 3-naphthylindoles in high yield. Furthermore, the other direct coupling of benzofuran, pyrrole or furan with 1-diazonaphthalene-2-(1H)-ones afforded 2- or 3-naphthyl substituted heterocycles. |
