| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 가을 (10/20 ~ 10/22, 경주컨벤션센터) |
| 권호 |
46권 2호 |
| 발표분야 |
Korea-Australia Joint Symposium: Functional Macromolecules for Advanced Applications (English) |
| 제목 |
Dendronised Polymers as a Delivery Platform |
| 초록 |
Dendronised polymers represent a highly uniform class of grafted macromolecules that are useful in a number of biological applications. The dendronised polymer architecture consists of a macromolecular backbone to which monodisperse, branched molecules (dendrons) are attached. We have prepared dendronised polymers with a high level of control, including the engineering of regular point defects within the dendron structure to investigate the effects of flexibility and charge distribution in the delivery of genetic cargo. I will discuss our work using these materials and describe their application to biological systems, including intracellular delivery of nucleic acids and proteins, single-cell sequencing, and as a highly tunable platform for preparing hydrogels. |
| 저자 |
Cameron W. Evans |
| 소속 |
The Univ. of Western Australia |
| 키워드 |
- |
| E-Mail |
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